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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2b50a2f6e89cafb51fc75ee7b306017ebffd3bc7a63c652f50e7b0a79076815' 
  AND token = 'xc5UIZE+F05UbSCwKZJlSUx/2QaOuEoqeI3XwSCiC6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}