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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '007341ad7abc12972ec008a5866a674b731be02bb9c41e01a425ebb7819040c9' 
  AND token = 'M8jL5WcKY0eEdMZwRYpRrWF62IUoP0IDCSyWT4BLY1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}