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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e56df16868d8852d542a048c5bd5848e505be130b309c5e4ac47a2234e6c13' 
  AND token = 'EjjBWGwfRLgtH9M8Zla1nmhuJI8En1yUidZZ1sGazrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}