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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '374b1d06940811e50e10a2fc356381f6d8c3076a921d00c0053518c73931c37f' 
  AND token = '8xecIuvqBaGEPa7hPJ9m+IDHITk7C4Rz6No2RWRWz8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}