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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00880e05351531fb1a6c1c4fdbcb5868e384f0b742f481a09f48efc0a758a399' 
  AND token = 'yZcl3ZL3iVQZvo3Z/DafbnsoKe8+hjw8Pk8py4btYTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}