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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4aebd7ebb6fa2684d3c5f439f34c9780d39b0e0ac3da572d46da66bb9420295' 
  AND token = '5wibCMsjLAMbApnBtb5YdireEWlO8ZbO4/9diNA2fBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}