SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433bcefe966b3f03badddb6018a1dbad7cc36e4900744fc6b76937a24a92b6cd' 
  AND token = 'jjUF8W4OM9/sQ5WxvbEUBOB1aNzx0I1zllcjeQsIvDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}