SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5cbb1da0d427b62916cf3cafb615c62bb2aab3d1a28481664aaa49741f7911f' 
  AND token = 'I95QMKsUSWb5qTWiHwLNhrgSARohbDS2m634ghXZ+iA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}