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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65879850911a96e6dc50e04ec8cd5a2214166ff1211ba5f8b5c20f6d137c6f80' 
  AND token = '/fQRF3X91GPMk6+V3e36RocwSaJLDLdl0xKAuleY4h8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}