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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a450575c916201998de1a5e8763c97ebe67c381ee0fc2bc8f7d9fb6b5b52e5' 
  AND token = 'Wh6/RqTV49lBFo0xZNu32nXIxRbaOXoA7qvXVZ0WIyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}