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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fa927e2dd547f35667c5460b7fc3f0e0f50f144febf834287787d4c74363aed' 
  AND token = 'Ar+sypcFIw2Viuvjcx3msVpL2oKlQcsEcLGD8WGlDLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}