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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb9ca6eeaf4a0bce9f0f015d1b4e5d853b483463938d10d8336cde9a0092c9e' 
  AND token = '2lS+3GSjcA5PPOqP2yGOKg6SxPE/dAXHTw0xIMFtLaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}