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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '709154d1061bc50195ce1693f8ab782a9256482e271284058082eb9122c488fc' 
  AND token = 'aOO6VoRiEIOC6+BlEXjkI3nHaLR+pM1FfN9rhE9kjOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}