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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d25ef2781c0c378c4cd8c72825fb69d8464991f0496fd39c9c225d3f4bc6343' 
  AND token = 'Ia4JCHtDPHl0FyGBa6m29TFSGBN6iaQ5cLr7TqtgyBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}