SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a952d8f70391c2c5496753a3a88d0e03c1a064178205e33c1964c53b40c9727' 
  AND token = 'pFLYct3kC8HgTtCNHpcfPk65lgWppypO5h/p0iKvPEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}