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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a3ca5729e8c10e11580d3dc0674c87377b391c1d687af724f607526b8ea0ca6' 
  AND token = 'I1p41kqtUWPZPMw/Zn21BLFxYu5CnHWBwOexakmIyto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}