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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c2c58a07ba8be05029426b42b4a88f508821a60de29dd11edd78d07b61e78e' 
  AND token = '4y1WAaxgIQtD2+seYTj6xIak9RvoCSgpHB8dqTthuo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}