SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17e4755e9521f2d8842896139b4c56ce245bd7abfbe6922bfe665c6cedaede1c' 
  AND token = 'D2W3zRUEPhKKV47HFJ0u51bKeHWwuO7cD7GvOV8dhgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}