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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c4d47149b6549a08d67a90d912ddb5183ebe4d3418c5e50659d202c40694dfd' 
  AND token = 'IM8IP+H/LNopjrv6uu/NK+VXJjLWl+JQXL+X4FC5rKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}