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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '553a3a8c16736fe8929eb4fa1217496d1e7c8b2d95d6e7c21b3745298c3f3edb' 
  AND token = 'UZ6vxH/DNvsbfc/LEcwHF310rU5LC8vSytaqQ/G8/dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}