SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053b111410ec6b55e74da56d034acd2c55deb88d06ef575e9358832427b754c3' 
  AND token = '+cgOcFAFLDXzGC095XcMEZ/nvSUf4gNtY7gPH5XoO1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}