SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '440f98bd3f778b977efcc820829e0b1c41a4ba153409fb245e718830b42cd562' 
  AND token = '0MtCAZq6pCnbPWWj4pvvdog5c16i4aAvPgkMDkPR0Pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}