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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bfa091afb374f69b142a46074fa8d23a1bac814d50f84adf645399a7ef6062a' 
  AND token = 'PI+D3LSZd8pUF/47mHY1VR1CPYcUPrMc7BWsPEIA01w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}