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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e085eeb0a4894ee9e2876920287d579fbb50be07b374f3b5cdbe42b6aa5a2f0c' 
  AND token = 'L2M6N+DuWvKF0lkr0FxCGNBIiv6oJmpodAqpOit+eeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}