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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c58e12e0db9c713d1bfd1784ab3ed8aee8a68d11e3c151319747eae7fc8d121' 
  AND token = '+gROYe4AVmuEAhKKEqpJU11G+EhS3HHy2uxf14bo1Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}