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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7537407aa6f250c2f69d12aded54549ce872d2986b6f6983a8c91cba5b900561' 
  AND token = '0+BArS8dbz1zFM1e6/yek1dhZmuS7XOKLxtw13yz7GU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}