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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96c63256aaf6c5f056ed234ae264197cac33926a850a8bf2a99469208573a758' 
  AND token = 'DFgEmY/I63vD63DhBzGcRp05PbkAqQbz9skdC5o6NXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}