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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f96825e23a2a0ad864210f49902bd23642db2c2cb1ee7be5daf32ca0f0700d' 
  AND token = 'G46mXp3Nicce/8c81zPlrGLkAXX1kbyMSyOiJ5kTiGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}