SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ffcdebf48a6133aaf424b640f291ccd64819f741ff0a3288dee1d5d3cea1079' 
  AND token = 't73GINhgj8GCqio1hnh6fLn/kBzK7OdcCamiBw+Ean4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}