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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2e33a1a2a115afd401677a966b2f78dcc2e3a3a0a6e6aa26dd2be10eff24876' 
  AND token = 'rUa9xEZLoFjh4C4xoMq2hJwBS6EjCztSwUY1vV7doQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}