SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45fe16067cee24bc922143d721690a20fa8c5d90c1e92a53888b49880234ca29' 
  AND token = 'rc+xSo8pZnwblTx/UnCigg1rXD4WME8NlI1XH7IDrcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}