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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15cf6aee1124394cc04323d65ee78f60a9fb48a4a4b9dcb24b8554dd4e63a7df' 
  AND token = 'S+Cb+SPCv835RByrCu+6UV3fNtguywclWxrIob1dh14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}