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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6c6cd64cc722d1ec67122af62d2301be902b2c35b5c8d6e797e359babbbe7c8' 
  AND token = 'P4k/AdvEkn94YN8YUumA+xnYmolFM8Ns3xjNOCrAIsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}