SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dd7588a1031affd362642e95b8f55a1143cec43e9c7bdfc494c66f42711bc2f' 
  AND token = 'bepllB6rNZomWGyz2uPDmE52JchMnYlWNSQeXpg4TQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}