SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c22b2c5d55cd0efc1d161bad937ba17b3a5069bb852a908ef540d6f0152f5c2a' 
  AND token = 'Uj7KlufTNO3AAhiNlZbjAgqkttzVED9ZM0fNWUlBOiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}