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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad9d6bd86b159ad3ea09a1c9ec55e09b8882322303d251c68853b14d0f6cd7e' 
  AND token = 'NZgz0EyY6wmUfpcSlmtBat1FIi2I2SUyCdMmYoBHNAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}