SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6734754168fe062792814a34d528b0c80ff825c4a0092f9f218f4072b96b4af1' 
  AND token = '6p2oh4Y9OkPO5uayeuy143WIBcm/nAsy6WNbSlumnGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}