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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a08860ae1f543c93f4f54593eb13d8cba88c44aff669d843a2ff5075f4f537c' 
  AND token = '/74uz7Den6K4AUMyCRzXI1kYu0E4MEZnJT/Uu4ryfs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}