SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53759b7cf166da85ba47f572dd66324f79a9d89e79d34dcc90c04b39be924ca9' 
  AND token = '34Wa7dvZ2913Co3rNIZcXp80ak4UdW7MRBqLp2bhoF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}