SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001f76349f33372a8c0912a6a323a023df8cf17afc04a51117a08d509e57b4d8' 
  AND token = '+YpMPVd+xrIOaQSOjlgvCmYaUOW6VDiejxep44fSf24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}