SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa59c657bc4dbe96ca735df2f0aa610ec134207f3b88b9d3806a1d7e0fb35995' 
  AND token = 'qlGhKZ/z3wdoFrIQjpSER1DARsGzdSBO7V2uvYUxHCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}