SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26e90c653cde697b5240cf857bb121f29b53efe506e284173a25bb16c3eab2f3' 
  AND token = 'bTE04X3b8wM3Dgmwenq64UeaGFGu+aC5fsyCIWDYOus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}