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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4707c70073a3d452a896d1d1e9920585f3b8cdd76d1062df7e41a02056c27559' 
  AND token = 'F2OCMpLQZig/KujLRMNE9zclT6AK5DS40zUsuBCZJzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}