SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a4eb8da72ff81bc1a6474a141170d7eb1c9aa0f596512f18c8d114280c456ec' 
  AND token = '2xzxcKGEi13TwX7Ag5w/jFQvWrZZv+aM7PiHbfL1160=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}