SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '907c42df01ca1ae95063836dd9948d19da664da1cf666fd249c46fdadbebcbde' 
  AND token = '4jz153NcoWFbq8eCLLGizPhGtl9aMPS7DdX+QM+rZYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}