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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eaa616a2a0b09712a96f02b9a632af11f686505b2d81b725b119b36dd8ad474' 
  AND token = 'gIEN8cetc2pNNC4wmxzEQCRiw5SvTrovG3RARwz6iCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}