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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a8a263186fa21a8feb076e5da8c7055474bae39ad6dc26965b1b7d454080912' 
  AND token = '+hxtI9zT4Pq+9sSaDHf8ERHFNvsWj1ScUE4yJX+R5Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}