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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3e0855e97b55decf68b396f4c058c1a3c828b419dc282bd631c1244953b5863' 
  AND token = 'mhAQsXKBDpD/2ePeb4G25BxIC4SPP4DyL24VaTLbSDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}