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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a702305da952e5e92c9d28925cd82b9ff45381699d09d4e81db9db9e82952c' 
  AND token = '6j0ZxdKZ1QHUY/dfLMXcrREbPpTqF0seOpFdm11a/hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}