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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '175444f9dcd0ccaf5c42147e2b3e27d0ab7083f2caddf6024e87d31ca1cd78e5' 
  AND token = 'RZuNh7MlYiZ3kgtHNk8H9s+8QwVKwHGE1gkc4G95uSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}